All you need to know about the new "Zika" virus disease

          Introduction
    Zika virus is an emerging mosquito-borne virus that was first identified in
Uganda in 1947 in rhesus monkeys through a monitoring network of
sylvatic yellow fever. It was subsequently identified in humans in 1952 in
Uganda and the United Republic of Tanzania. Outbreaks of Zika virus
disease have been recorded in Africa, the Americas, Asia and the Pacific.
  • Genre: Flavivirus
  • Vector: Aedes mosquitoes (which usually bite during the morning and late afternoon/evening hours)
  • Reservoir: Unknown
   (*vector in biological term is the organism or let's say the thing that infects people the with the virus or carries the virus around)


          Signs and Symptoms
    The incubation period (the time from exposure to symptoms) of Zika
virus disease is not clear, but is likely to be a few days. The symptoms
are similar to other arbovirus infections such as dengue, and include
fever, skin rashes, conjunctivitis, muscle and joint pain, malaise, and
headache. These symptoms are usually mild and last for 2-7 days.

           Potential complications of Zika virus disease
    During large outbreaks in French Polynesia and Brazil in 2013 and 2015
respectively, national health authorities reported potential neurological
and auto-immune complications of Zika virus disease. Recently in Brazil,
local health authorities have observed an increase in Guillain-Barré
syndrome which coincided with Zika virus infections in the general
public, as well as an increase in babies born with microcephaly in
northeast Brazil. Agencies investigating the Zika outbreaks are finding an
increasing body of evidence about the link between Zika virus and
microcephaly. However, more investigation is needed to better
understand the relationship between microcephaly in babies and the Zika
virus. Other potential causes are also being investigated.

          Transmission
    Zika virus is transmitted to people through the bite of an infected
mosquito from the Aedes genus, mainly Aedes aegypti in tropical regions.
This is the same mosquito that transmits dengue, chikungunya and
yellow fever. However, sexual transmission of Zika virus has been
described in 2 cases, and the presence of the Zika virus in semen in 1
additional case.
    Zika virus disease outbreaks were reported for the first time from the
Pacific in 2007 and 2013 (Yap and French Polynesia, respectively), and in
2015 from the Americas (Brazil and Colombia) and Africa (Cabo Verde).
In addition, more than 13 countries in the Americas have reported
sporadic Zika virus infections indicating rapid geographic expansion of
Zika virus.

          Diagnosis
    Infection with Zika virus may be suspected based on symptoms and
recent history (e.g. residence or travel to an area where Zika virus is
known to be present). Zika virus diagnosis can only be confirmed by
laboratory testing for the presence of Zika virus RNA in the blood or
other body fluids, such as urine or saliva.

           Prevention 
    Mosquitoes and their breeding sites pose a significant risk factor for
Zika virus infection. Prevention and control relies on reducing
mosquitoes through source reduction (removal and modification of
breeding sites) and reducing contact between mosquitoes and people.
This can be done by using insect repellent regularly; wearing clothes
(preferably light-coloured) that cover as much of the body as possible;
using physical barriers such as window screens, closed doors and
windows; and if needed, additional personal protection, such as sleeping
under mosquito nets during the day. It is extremely important to empty,
clean or cover containers regularly that can store water, such as buckets,
drums, pots etc. Other mosquito breeding sites should be cleaned or
removed including flower pots, used tyres and roof gutters. Communities
must support the efforts of the local government to reduce the density of
mosquitoes in their locality.
    Repellents should contain DEET (N, N-diethyl-3-methylbenzamide),
IR3535 (3-[N-acetyl-N-butyl]-aminopropionic acid ethyl ester) or icaridin
(1-piperidinecarboxylic acid, 2-(2-hydroxyethyl)-1-methylpropylester).
Product label instructions should be strictly followed. Special attention
and help should be given to those who may not be able to protect
themselves adequately,  such as young children, the sick or elderly.
    During outbreaks, health authorities may advise that spraying of
insecticides be carried out. Insecticides recommended by the WHO
Pesticide Evaluation Scheme may also be used as larvicides to treat
relatively large water containers.
    Travellers should take the basic precautions described above to protect
themselves from mosquito bites.

          Treatment
    Zika virus disease is usually relatively mild and requires no specific
treatment. People sick with Zika virus should get plenty of rest, drink
enough fluids, and treat pain and fever with common medicines. If
symptoms worsen, they should seek medical care and advice. There is
currently no vaccine available.


WHO is supporting countries to control Zika virus disease through:
  • Define and prioritize research into Zika virus disease by convening experts and partners.
  • Enhance surveillance of Zika virus and potential complications.
  • Strengthen capacity in risk communication to help countries meet their commitments under the International Health Regulations.
  • Provide training on clinical management, diagnosis and vector control including. through a number of WHO Collaborating Centres.
  • Strengthen the capacity of laboratories to detect the virus.
  • Support health authorities to implement vector control strategies aimed at reducing Aedes mosquito populations such as providing larvicide to treat still water sites that cannot be treated in other ways, such as cleaning, emptying, and covering them.
  • Prepare recommendations for clinical care and follow-up of people with Zika virus, in collaboration with experts and other health agencies. 

Key facts
  • Zika virus disease is caused by a virus transmitted by Aedes mosquitoes.
  • People with Zika virus disease usually have symptoms that can include mild fever, skin rashes, conjunctivitis, muscle and joint pain, malaise or headache. These symptoms normally last for 2-7 days.
  • There is no specific treatment or vaccine currently available.
  • The best form of prevention is protection against mosquito bites.
  • The virus is known to circulate in Africa, the Americas, Asia and the Pacific.

 Source :    World Health Organization


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